Ways of dealing with tumours that move as the patient breathes: image the motion, treat only in part of the breathing cycle, hold the breath, or chase the tumour with the beam.
Lung, liver, pancreas and breast targets move by a centimetre or more with breathing. Four-dimensional CT captures the motion so the target volume can include it or be defined at one phase; respiratory gating switches the beam on only during that phase; deep-inspiration breath-hold freezes the anatomy and, in left breast treatment, moves the heart away from the beam; and real-time tracking with fiducial markers or MRI moves the beam or couch with the tumour. Motion management is what makes stereotactic body radiotherapy safe for small mobile targets.
Measure or constrain respiratory motion so the planned dose lands on the target rather than on the tissue it moves through.
Breath-hold for left breast radiotherapy can be delivered without special breathing equipment across ordinary NHS departments, and lowers heart dose in almost everyone selected for it.
The heart benefit of breath-hold is a projection from dose: it rests on the dose-risk relationship measured by Darby and colleagues, not on a trial counting heart attacks in women treated with and without breath-hold.
Query for this technology: (TITLE:"Respiratory motion management" OR ABSTRACT:"Respiratory motion management" OR TITLE:"4D-CT, gating, breath-hold, tracking" OR ABSTRACT:"4D-CT, gating, breath-hold, tracking") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Respiratory motion management (4D-CT, gating, breath-hold, tracking), not a curated reading list.
Shares C-RAD, Vision RT, The UK HeartSpare Study (Stage II): multicentre evaluation of a voluntary breath-hold technique in patients receiving breast radiotherapy, Let the patient see their own breath-hold on a screen or in video glasses and the tags radiation-wave1, precision.
Shares MR-guided adaptive radiotherapy, Precision roadmap: margins measured in millimetres → tests that find a target → doses fitted to the person → precision that changes outcomes, IMRT / IGRT (modern external beam) and the tags radiation-wave1, precision.
Shares CyberKnife robotic radiosurgery, SBRT / SABR (stereotactic radiotherapy), IMRT / IGRT (modern external beam) and the tags radiation-wave1, precision.
Shares IMRT / IGRT (modern external beam) and the tags radiation-wave1, precision.
Shares IMRT / IGRT (modern external beam) and the tags radiation-wave1, precision.
Shares the tags radiation-wave1, precision.
Shares C-RAD, Vision RT, Let the patient see their own breath-hold on a screen or in video glasses, Respiratory gating and tumour tracking systems (RPM, ABC, Calypso, Synchrony) and the tag precision.
Shares CyberKnife robotic radiosurgery, SBRT / SABR (stereotactic radiotherapy), Non-small-cell lung cancer and the tag radiation-wave1.
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