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A single very high dose, or a few doses, aimed at a small brain or spine target with millimetre precision, replacing whole-brain radiotherapy for most brain metastases.
Lars Leksell treated the first patients with the Gamma Knife in 1968 using converging cobalt-60 beams; today the same idea is delivered by dedicated Gamma Knife units, the robotic CyberKnife and conventional linacs fitted with fine collimators and image guidance. Radiosurgery treats brain metastases, meningiomas, vestibular schwannomas, arteriovenous malformations and, increasingly, spinal metastases. Randomised trials showed that treating brain metastases with radiosurgery alone preserves memory and thinking better than adding whole-brain radiotherapy, with no loss of survival.
Many narrow beams converge on a small target so the dose falls off steeply within millimetres; rigid immobilisation and image guidance keep the target within the beam.
Query for this technology: (TITLE:"Stereotactic radiosurgery" OR ABSTRACT:"Stereotactic radiosurgery" OR TITLE:"Gamma Knife, CyberKnife, linac SRS" OR ABSTRACT:"Gamma Knife, CyberKnife, linac SRS") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Stereotactic radiosurgery (Gamma Knife, CyberKnife, linac SRS), not a curated reading list.
Shares CyberKnife robotic radiosurgery, SBRT / SABR (stereotactic radiotherapy), IMRT / IGRT (modern external beam) and the tags radiation-wave1, precision.
Shares Defining the optimal planning target volume in image-guided stereotactic radiosurgery of brain metastases: results of a randomized trial, IMRT / IGRT (modern external beam) and the tags radiation-wave1, precision.
Shares CyberKnife robotic radiosurgery, SBRT / SABR (stereotactic radiotherapy), IMRT / IGRT (modern external beam) and the tags radiation-wave1, precision.
Shares Patient positioning and surface guidance systems (AlignRT, Catalyst, ExacTrac Dynamic), IMRT / IGRT (modern external beam) and the tags radiation-wave1, precision.
Shares Brain and spinal cord tumours (all types) and the tags radiation-wave1, precision.
Shares IMRT / IGRT (modern external beam) and the tags radiation-wave1, precision.
Shares IMRT / IGRT (modern external beam) and the tags radiation-wave1, precision.
Shares the tags radiation-wave1, precision.
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