A research blood test that looks for six digestive-system cancers at once and predicts which organ the signal comes from.
Kandimalla et al. (Clinical Cancer Research 2021) validated the panel in 300 cell-free DNA specimens: a pan-gastrointestinal panel detected all six cancers (colorectal, hepatocellular, oesophageal squamous and adenocarcinoma, gastric, pancreatic) with an area under the curve of 0.88, and the EpiPanGI Dx tissue-of-origin panel predicted the organ with accuracy of 0.85 to 0.95 for most. It is an academic assay without regulatory status.
Targeted bisulphite sequencing of 67,832 methylated regions chosen from tumour tissue, with panels to detect any digestive cancer and to predict which organ it is in.
1.EpiPanGI Dx slips into a pocket on its target.
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Query for this drug: (TITLE:"EpiPanGI Dx" OR ABSTRACT:"EpiPanGI Dx") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about EpiPanGI Dx, not a curated reading list.
Shares Cell-free DNA methylation tests, Multi-cancer early detection (MCED), Oesophageal cancer, Liquid biopsy (ctDNA) and the tags test, mced.
Shares Cell-free DNA methylation tests, Multi-cancer early detection (MCED), Liquid biopsy (ctDNA) and the tags test, mced.
Shares Multi-cancer early detection (MCED), Liquid biopsy (ctDNA) and the tags test, mced.
Shares Multi-cancer early detection (MCED), Liquid biopsy (ctDNA) and the tags test, mced.
Shares Cell-free DNA methylation tests, Multi-cancer early detection (MCED), Liquid biopsy (ctDNA) and the tags test, mced.
Shares Multi-cancer early detection (MCED), Liquid biopsy (ctDNA) and the tags test, mced.
Shares Cell-free DNA methylation tests, Multi-cancer early detection (MCED), Liquid biopsy (ctDNA) and the tags test, mced.
Shares Multi-cancer early detection (MCED), Liquid biopsy (ctDNA) and the tags test, mced.
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