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A phase 2 trial of cemiplimab in colorectal cancer, run by John Strickler, M.D., not yet recruiting.
Cemiplimab With Fianlimab for Resectable Non-Metastatic Colon Cancer is a phase 2, interventional study registered as NCT07224022 by John Strickler, M.D., with a registry enrolment figure of 24 participants, started 2026-10-01 and due to reach its primary completion in 2028-12-31. Interventions recorded: Cemiplimab + Fianlimab [Fixed Dose Combination (FDC)]. Conditions listed: Colon Cancer. Primary outcome: Feasibility of treatment with cemiplimab and fianlimab before surgery; Safety of treatment with cemiplimab and fianlimab before surgery. Colorectal eligibility wording from the registry: "Histologically and/or cytologically documented adenocarcinoma of the colon". No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Regeneron, Cemiplimab, T-cell exhaustion and CAR-T persistence, Colon cancer (adenocarcinoma of the colon) and the tag colorectal-deep-dive.
Shares Cemiplimab, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Immune checkpoint inhibitors and the tag colorectal-deep-dive.
Shares Regeneron, Cemiplimab, T-cell exhaustion and CAR-T persistence, Colon cancer (adenocarcinoma of the colon) and the tag colorectal-deep-dive.
Shares Regeneron, Cemiplimab, T-cell exhaustion and CAR-T persistence, Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Immune checkpoint inhibitors and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Immune checkpoint inhibitors and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Immune checkpoint inhibitors and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Immune checkpoint inhibitors and the tag colorectal-deep-dive.
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