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A German blood test sold through a private health insurance add-on, which claims to signal cancer of any type; its published evidence is small studies and case reports.
Zyagnum AG of Darmstadt markets PanTum Detect as tumour-independent (it does not say which organ) and states on its website that it is IVDR-certified under Regulation (EU) 2017/746 with notified body TÜV Rheinland (CE 0197). It is sold through the HanseMerkur Krebs-Scan insurance add-on, reported at about 238 euros a year for a 50-year-old (Pharmazeutische Zeitung, 10 August 2023); that is an insurance premium, not a test price.
The largest peer-reviewed study found (Saman et al., Cancer Biomarkers 2020) tested 62 patients with bile duct, pancreatic or colorectal cancer against 29 controls: the combined score was positive in all 62 and in none of the healthy controls, and in 7.7% of 13 people with inflammation. Other publications are case reports. Higher sensitivity and specificity figures circulating in news coverage could not be traced to a primary source.
Epitope detection in monocytes (EDIM): flow cytometry measures two markers, Apo10 and TKTL1, inside blood monocytes that have taken up tumour material, giving a tumour-independent score.
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Query for this drug: (TITLE:"PanTum Detect" OR ABSTRACT:"PanTum Detect" OR TITLE:"EDIM test" OR ABSTRACT:"EDIM test" OR TITLE:"EDIM-CS" OR ABSTRACT:"EDIM-CS") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about PanTum Detect, not a curated reading list.
Shares Proteomics & phosphoproteomics, Multi-cancer early detection (MCED), Liquid biopsy (ctDNA) and the tags test, mced.
Shares Proteomics & phosphoproteomics, Multi-cancer early detection (MCED), Liquid biopsy (ctDNA) and the tags test, mced.
Shares Proteomics & phosphoproteomics, Multi-cancer early detection (MCED), Liquid biopsy (ctDNA) and the tags test, mced.
Shares Multi-cancer early detection (MCED), Liquid biopsy (ctDNA) and the tags test, mced.
Shares Multi-cancer early detection (MCED), Liquid biopsy (ctDNA) and the tags test, mced.
Shares Proteomics & phosphoproteomics, Multi-cancer early detection (MCED), Liquid biopsy (ctDNA) and the tags test, mced.
Shares Proteomics & phosphoproteomics, Multi-cancer early detection (MCED), Liquid biopsy (ctDNA) and the tags test, mced.
Shares Multi-cancer early detection (MCED), Liquid biopsy (ctDNA) and the tags test, mced.
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