Before cancer spreads, distant organs are changed to become welcoming. A test for those changes would show which organ is at risk while a person still looks cancer-free.
Pre-metastatic niche formation involves tumour-derived exosome integrins, S100A8 and S100A9 induction, myeloid mobilisation and fibronectin deposition in the target organ. Candidate readouts exist (plasma S100A8/A9, exosomal integrin profiles, circulating LOX activity, neutrophil trajectories) but nobody has assembled them into a validated organ-specific risk assay.
Shares Are 90% of deaths from cancer caused by metastases?, Metastasis is understood least and studied last, Dormant cells and minimal residual disease, Liquid biopsy (ctDNA).
Shares Are 90% of deaths from cancer caused by metastases?, Metastasis is understood least and studied last, Dormant cells and minimal residual disease, Liquid biopsy (ctDNA).
Shares Are 90% of deaths from cancer caused by metastases?, Metastasis is understood least and studied last, Dormant cells and minimal residual disease, HR-positive / HER2-negative breast cancer.
Shares Are 90% of deaths from cancer caused by metastases?, Metastasis is understood least and studied last, HR-positive / HER2-negative breast cancer, Colorectal cancer.
Shares Are 90% of deaths from cancer caused by metastases?, Metastasis is understood least and studied last, Biomarkers are not validated or standardised, Liquid biopsy (ctDNA).
Shares Are 90% of deaths from cancer caused by metastases?, Metastasis is understood least and studied last, Biomarkers are not validated or standardised, Liquid biopsy (ctDNA).
Shares Are 90% of deaths from cancer caused by metastases?, Metastasis is understood least and studied last, HR-positive / HER2-negative breast cancer, Pancreatic ductal adenocarcinoma.
Shares Are 90% of deaths from cancer caused by metastases?, Metastasis is understood least and studied last, Colorectal cancer.
Every source this page cites, grouped by who published it. Grouping is read from the web address, not assigned by hand.
A source that has moved or gone is reported by the weekly link check. /audit/