{"slug":"trials-by-enrolment","title":"Trials by enrolment","basis":"Trials ordered by the number of people their record says were enrolled, randomised, analysed or treated.","metric":"Enrolment","context":"Phase and cancer","how":"Reads the enrolled field and the enrolledBasis field that says what the number counts (the registry figure by default, or the randomised, analysed, treated or registered population from the primary paper). Numbers from different bases are placed on one scale, so a registry total and a randomised count sit side by side. The context column gives the phase and the first cancer the trial names.","coverage":{"filled":5974,"of":6143,"what":"trials carry an enrolment figure","share":0.972},"total":5974,"top":50,"rows":[{"rank":1,"id":"agex","name":"AgeX","kind":"trial","route":"/trials/agex/","value":4000000,"metric":"4,000,000 enrolled","context":"Phase 3 · Breast cancer (all types)"},{"rank":2,"id":"ukctocs","name":"UKCTOCS","kind":"trial","route":"/trials/ukctocs/","value":202638,"metric":"202,638 enrolled","context":"Phase 3 · Ovarian cancer"},{"rank":3,"id":"kerala-oral-screening","name":"Kerala oral cancer visual screening trial (Trivandrum)","kind":"trial","route":"/trials/kerala-oral-screening/","value":191873,"metric":"191,873 enrolled","context":"Phase 3 · Head and neck squamous cell carcinoma"},{"rank":4,"id":"ukfss","name":"UK Flexible Sigmoidoscopy Screening Trial","kind":"trial","route":"/trials/ukfss/","value":170432,"metric":"170,432 randomised","context":"Phase 3 · Colorectal cancer"},{"rank":5,"id":"nottingham-fob","name":"Nottingham faecal occult blood screening trial","kind":"trial","route":"/trials/nottingham-fob/","value":152850,"metric":"152,850 randomised","context":"Phase 3 · Colorectal cancer"},{"rank":6,"id":"mumbai-via-screening","name":"Mumbai VIA cervical screening trial (Tata Memorial)","kind":"trial","route":"/trials/mumbai-via-screening/","value":151538,"metric":"151,538 enrolled","context":"Phase 3 · Cervical cancer"},{"rank":7,"id":"nhs-galleri","name":"NHS-Galleri","kind":"trial","route":"/trials/nhs-galleri/","value":142250,"metric":"142,250 randomised","context":"Phase 3 · Lung cancer (all types)"},{"rank":8,"id":"osmanabad-hpv-screening","name":"Osmanabad cervical screening trial (HPV testing vs cytology vs VIA)","kind":"trial","route":"/trials/osmanabad-hpv-screening/","value":131746,"metric":"131,746 enrolled","context":"Phase 3 · Cervical cancer"},{"rank":9,"id":"masai","name":"MASAI (Mammography Screening with Artificial Intelligence)","kind":"trial","route":"/trials/masai/","value":105934,"metric":"105,934 randomised","context":"Phase 3 · HR-positive / HER2-negative breast cancer"},{"rank":10,"id":"strive-grail","name":"STRIVE (GRAIL breast screening cohort)","kind":"trial","route":"/trials/strive-grail/","value":99481,"metric":"99,481 enrolled","context":"Observational study"},{"rank":11,"id":"nordicc","name":"NordICC (Nordic-European Initiative on Colorectal Cancer)","kind":"trial","route":"/trials/nordicc/","value":84585,"metric":"84,585 analysed","context":"Phase 3 · Colorectal cancer"},{"rank":12,"id":"istopmm","name":"iStopMM","kind":"trial","route":"/trials/istopmm/","value":75422,"metric":"75,422 enrolled","context":"Observational study · Multiple myeloma"},{"rank":13,"id":"funen-fob","name":"Funen faecal occult blood screening trial","kind":"trial","route":"/trials/funen-fob/","value":61933,"metric":"61,933 randomised","context":"Phase 3 · Colorectal cancer"},{"rank":14,"id":"fusion-singlera","name":"FuSion (Fudan and Singlera pan-cancer screening cohort)","kind":"trial","route":"/trials/fusion-singlera/","value":60000,"metric":"60,000 enrolled","context":"Observational study"},{"rank":15,"id":"screentrustcad","name":"ScreenTrustCAD","kind":"trial","route":"/trials/screentrustcad/","value":55581,"metric":"55,581 analysed","context":"Observational study · HR-positive / HER2-negative breast cancer"},{"rank":16,"id":"nlst-nelson","name":"NLST & NELSON (low-dose CT screening)","kind":"trial","route":"/trials/nlst-nelson/","value":53454,"metric":"53,454 enrolled","context":"Phase 3 · Non-small-cell lung cancer"},{"rank":17,"id":"ccss","name":"Childhood Cancer Survivor Study (CCSS)","kind":"trial","route":"/trials/ccss/","value":50000,"metric":"50,000 enrolled","context":"Observational study · Acute lymphoblastic leukaemia"},{"rank":18,"id":"reach-galleri-medicare","name":"REACH (Galleri in the Medicare population)","kind":"trial","route":"/trials/reach-galleri-medicare/","value":50000,"metric":"50,000 enrolled","context":"Phase not applicable"},{"rank":19,"id":"preempt-crc","name":"PREEMPT CRC","kind":"trial","route":"/trials/preempt-crc/","value":48995,"metric":"48,995 enrolled","context":"Observational study · Colorectal cancer"},{"rank":20,"id":"minnesota-fob","name":"Minnesota Colon Cancer Control Study","kind":"trial","route":"/trials/minnesota-fob/","value":46551,"metric":"46,551 randomised","context":"Phase 3 · Colorectal cancer"},{"rank":21,"id":"eclipse-shield","name":"ECLIPSE (Shield blood test)","kind":"trial","route":"/trials/eclipse-shield/","value":44467,"metric":"44,467 enrolled","context":"Observational study · Colorectal cancer"},{"rank":22,"id":"pathfinder-2","name":"PATHFINDER 2","kind":"trial","route":"/trials/pathfinder-2/","value":35883,"metric":"35,883 enrolled","context":"Observational study"},{"rank":23,"id":"vital","name":"VITAL (VITamin D and OmegA-3 TriaL)","kind":"trial","route":"/trials/vital/","value":25871,"metric":"25,871 enrolled","context":"Phase 3"},{"rank":24,"id":"falcon-registry","name":"Falcon Registry (Exact Sciences multi-cancer test real-world evidence)","kind":"trial","route":"/trials/falcon-registry/","value":25000,"metric":"25,000 enrolled","context":"Observational study"},{"rank":25,"id":"vanguard-study","name":"Vanguard Study (NCI Cancer Screening Research Network)","kind":"trial","route":"/trials/vanguard-study/","value":24000,"metric":"24,000 enrolled","context":"Platform trial"},{"rank":26,"id":"blue-c","name":"BLUE-C","kind":"trial","route":"/trials/blue-c/","value":20176,"metric":"20,176 enrolled","context":"Observational study · Colorectal cancer"},{"rank":27,"id":"clearnote-multi-cancer-epigenomics","name":"ClearNote Health multi-cancer epigenomics study","kind":"trial","route":"/trials/clearnote-multi-cancer-epigenomics/","value":20000,"metric":"20,000 enrolled","context":"Observational study"},{"rank":28,"id":"precede","name":"PRECEDE","kind":"trial","route":"/trials/precede/","value":20000,"metric":"20,000 enrolled","context":"Observational study · Pancreatic ductal adenocarcinoma"},{"rank":29,"id":"scan-b","name":"SCAN-B (Sweden Cancerome Analysis Network - Breast)","kind":"trial","route":"/trials/scan-b/","value":20000,"metric":"20,000 enrolled","context":"Observational study · Breast cancer (all types)"},{"rank":30,"id":"aspree","name":"ASPREE (ASPirin in Reducing Events in the Elderly)","kind":"trial","route":"/trials/aspree/","value":19114,"metric":"19,114 enrolled","context":"Phase 3"},{"rank":31,"id":"patricia","name":"PATRICIA","kind":"trial","route":"/trials/patricia/","value":18644,"metric":"18,644 randomised","context":"Phase 3 · Cervical cancer"},{"rank":32,"id":"nct06041061","name":"A Study to Evaluate the Efficacy, Safety, and Immunogenicity of SCT1000 in Healthy Women Aged 18-45 Years","kind":"trial","route":"/trials/nct06041061/","value":18000,"metric":"18,000 enrolled","context":"Phase 3 · Metastatic cancer (cancer that has spread)"},{"rank":33,"id":"goteborg-2","name":"GÖTEBORG-2 (MRI-based prostate cancer screening)","kind":"trial","route":"/trials/goteborg-2/","value":17980,"metric":"17,980 enrolled","context":"Phase 3 · Prostate cancer"},{"rank":34,"id":"iarc-india-hpv-dose-study","name":"IARC India HPV vaccine dose study (one, two or three doses)","kind":"trial","route":"/trials/iarc-india-hpv-dose-study/","value":17729,"metric":"17,729 enrolled","context":"Observational study · Cervical cancer"},{"rank":35,"id":"profound-mced","name":"PROFOUND (Weihe multi-omic multi-cancer case-control study)","kind":"trial","route":"/trials/profound-mced/","value":16666,"metric":"16,666 enrolled","context":"Observational study"},{"rank":36,"id":"transform-prostate","name":"TRANSFORM","kind":"trial","route":"/trials/transform-prostate/","value":16000,"metric":"16,000 enrolled","context":"Phase 3 · Prostate cancer"},{"rank":37,"id":"ccga","name":"CCGA (Circulating Cell-free Genome Atlas)","kind":"trial","route":"/trials/ccga/","value":15254,"metric":"15,254 enrolled","context":"Observational study"},{"rank":38,"id":"jinling-cohort","name":"Jinling Cohort (MERCURY multi-omic test in Nanjing)","kind":"trial","route":"/trials/jinling-cohort/","value":15000,"metric":"15,000 enrolled","context":"Observational study"},{"rank":39,"id":"cadence-mirxes","name":"Project CADENCE (Mirxes multi-cancer blood test)","kind":"trial","route":"/trials/cadence-mirxes/","value":15000,"metric":"15,000 enrolled","context":"Observational study"},{"rank":40,"id":"reflection-galleri","name":"REFLECTION (Galleri real-world learning programme)","kind":"trial","route":"/trials/reflection-galleri/","value":14633,"metric":"14,633 enrolled","context":"Observational study"},{"rank":41,"id":"predict-overc","name":"PREDICT (Burning Rock pan-cancer early detection project)","kind":"trial","route":"/trials/predict-overc/","value":14026,"metric":"14,026 enrolled","context":"Observational study"},{"rank":42,"id":"nct05262010","name":"A Phase III Clinical Trial of a 11-valent Recombinant Human Papillomavirus Vaccine (Hansenulapolymorpha) in Chinese Women Aged 9-45 Years","kind":"trial","route":"/trials/nct05262010/","value":13500,"metric":"13,500 enrolled","context":"Phase 3 · Metastatic cancer (cancer that has spread)"},{"rank":43,"id":"idea-collaboration","name":"IDEA collaboration","kind":"trial","route":"/trials/idea-collaboration/","value":12834,"metric":"12,834 analysed","context":"Phase 3 · Colorectal cancer"},{"rank":44,"id":"summit-lung","name":"SUMMIT (lung health check study)","kind":"trial","route":"/trials/summit-lung/","value":12773,"metric":"12,773 registered","context":"Observational study · Non-small-cell lung cancer"},{"rank":45,"id":"prevent-overc","name":"PREVENT (OverC in people without symptoms)","kind":"trial","route":"/trials/prevent-overc/","value":12500,"metric":"12,500 enrolled","context":"Phase not applicable"},{"rank":46,"id":"nct05055908","name":"Efficacy and Biomarker Development for Lung Cancer Treated With Immune Checkpoint Inhibitors","kind":"trial","route":"/trials/nct05055908/","value":12000,"metric":"12,000 enrolled","context":"Phase 3 · Lung cancer (all types)"},{"rank":47,"id":"stampede","name":"STAMPEDE","kind":"trial","route":"/trials/stampede/","value":11992,"metric":"11,992 enrolled","context":"Platform trial · Prostate cancer"},{"rank":48,"id":"prescient-cams","name":"PRESCIENT (pan-cancer early-stage detection, Chinese Academy of Medical Sciences)","kind":"trial","route":"/trials/prescient-cams/","value":11879,"metric":"11,879 enrolled","context":"Observational study"},{"rank":49,"id":"add-aspirin","name":"Add-Aspirin","kind":"trial","route":"/trials/add-aspirin/","value":11000,"metric":"11,000 enrolled","context":"Phase 3 · Colorectal cancer"},{"rank":50,"id":"tailorx","name":"TAILORx","kind":"trial","route":"/trials/tailorx/","value":10273,"metric":"10,273 enrolled","context":"Phase 3 · HR-positive / HER2-negative breast cancer"}]}