{"slug":"mced","tag":"mced","variants":["mced"],"description":"No description yet","count":31,"kinds":{"drug":27,"person":3,"roadmap":1},"related":[{"slug":"test","tag":"test","shared":26},{"slug":"early-detection","tag":"early-detection","shared":3},{"slug":"liquid-biopsy","tag":"liquid-biopsy","shared":2},{"slug":"colorectal","tag":"colorectal","shared":1},{"slug":"ctdna","tag":"ctdna","shared":1},{"slug":"mrd","tag":"mrd","shared":1},{"slug":"precision","tag":"precision","shared":1},{"slug":"prostate","tag":"prostate","shared":1}],"records":[{"id":"galleri","kind":"drug","name":"Galleri","route":"/drugs/galleri/","status":"phase-3","tldr":"GRAIL's blood test that looks for a signal from more than 50 cancers at once; an FDA advisory panel voted in its favour in September 2026, but in the NHS-Galleri randomised trial three yearly tests did not reduce the number of cancers found at a late stage."},{"id":"nickolas-papadopoulos","kind":"person","name":"Nickolas Papadopoulos","route":"/people/nickolas-papadopoulos/","tldr":"Co-developed CancerSEEK, the blood test that showed multi-cancer early detection is possible, and ran the first prospective screening study of it."},{"id":"eric-klein","kind":"person","name":"Eric A. Klein","route":"/people/eric-klein/","tldr":"Urologist who led the CCGA study validating the Galleri methylation-based multi-cancer detection test."},{"id":"deb-schrag","kind":"person","name":"Deborah Schrag","route":"/people/deb-schrag/","tldr":"Led PATHFINDER, the first prospective study of a multi-cancer blood test in practice, and the PROSPECT rectal cancer trial."},{"id":"ctdna-tests","kind":"roadmap","name":"ctDNA tests roadmap: from a curiosity in plasma to blood tests that decide treatment","route":"/roadmaps/ctdna-tests/","tldr":"Blood carries fragments of tumour DNA. This roadmap follows the tests that read them, from the first sighting in 1948 to blood tests that now choose a drug, spare chemotherapy, or screen for many cancers at once, and it lists the readouts to watch next."},{"id":"cancerguard","kind":"drug","name":"Cancerguard","route":"/drugs/cancerguard/","status":"emerging","tldr":"Exact Sciences' multi-cancer blood test, sold since 2025 as a lab test that has not been through FDA approval; it says whether a cancer signal is present but not where, so a positive result leads to scans."},{"id":"shield-mcd","kind":"drug","name":"Shield MCD (Shield Multi-Cancer Detection)","route":"/drugs/shield-mcd/","status":"emerging","tldr":"Guardant Health's blood test for ten cancers, offered in the United States as an add-on report to its bowel cancer blood test and chosen by the US National Cancer Institute for its first randomised study of such tests."},{"id":"avantect-mcd","kind":"drug","name":"Avantect Multi-Cancer Detection Test","route":"/drugs/avantect-mcd/","status":"emerging","tldr":"ClearNote Health's blood test for several cancers, one of the two tests in the US National Cancer Institute's randomised Vanguard study, with no published performance figures yet."},{"id":"harbinger-resolve","kind":"drug","name":"RESOLVE (Harbinger Health)","route":"/drugs/harbinger-resolve/","status":"emerging","tldr":"Harbinger Health's blood test meant for the weeks between a doctor suspecting cancer and a diagnosis, pointing to where in the body a cancer may be; it is not offered as a screening test for well people."},{"id":"cancerseek","kind":"drug","name":"CancerSEEK","route":"/drugs/cancerseek/","status":"historic","tldr":"The Johns Hopkins blood test that first showed one draw could find several cancers and point to the organ; its approach passed to Thrive Earlier Detection and then to Exact Sciences, whose Cancerguard test followed."},{"id":"onetest","kind":"drug","name":"OneTest for Cancer","route":"/drugs/onetest/","status":"emerging","tldr":"A low-cost blood test from 20/20 BioLabs that measures a panel of protein tumour markers and is sold in the United States as a laboratory test without FDA review."},{"id":"novelna-protein-test","kind":"drug","name":"Novelna sex-specific protein test","route":"/drugs/novelna-protein-test/","status":"emerging","tldr":"An experimental blood test that reads a handful of proteins, with different panels for men and women, to find many early cancers; so far it has been tried only on a few hundred stored samples."},{"id":"adela-mced","kind":"drug","name":"Adela multi-cancer methylome test","route":"/drugs/adela-mced/","status":"emerging","tldr":"Adela's blood test in development for 20 cancer types, built on reading DNA methylation across the whole genome; no peer-reviewed screening results yet."},{"id":"gagome-mced-test","kind":"drug","name":"Elypta GAGome multi-cancer test","route":"/drugs/gagome-mced-test/","status":"emerging","tldr":"A test in development from Elypta in Sweden that reads sugar molecules in urine and blood rather than DNA, aiming to flag many cancers including some that DNA tests find hard to see."},{"id":"carcimun-test","kind":"drug","name":"Carcimun test","route":"/drugs/carcimun-test/","status":"emerging","tldr":"A German blood test that measures how blood proteins change shape; the only studies are small, run with the inventor, and do not say how often it finds early cancers."},{"id":"dxcover-cancer-liquid-biopsy","kind":"drug","name":"Dxcover Cancer Liquid Biopsy","route":"/drugs/dxcover-cancer-liquid-biopsy/","status":"emerging","tldr":"A Glasgow company's blood test that shines infrared light through serum to look for cancer; it is sold in the UK for brain tumours, and the multi-cancer version is still in study."},{"id":"pantum-detect","kind":"drug","name":"PanTum Detect","route":"/drugs/pantum-detect/","status":"emerging","tldr":"A German blood test sold through a private health insurance add-on, which claims to signal cancer of any type; its published evidence is small studies and case reports."},{"id":"nu-q-cancer","kind":"drug","name":"Nu.Q Cancer","route":"/drugs/nu-q-cancer/","status":"emerging","tldr":"VolitionRx's blood test that measures DNA packaging released by dying cells; a version is sold for dogs, and the human multi-cancer test is at preprint stage."},{"id":"thromboseq","kind":"drug","name":"thromboSeq (tumour-educated platelet RNA)","route":"/drugs/thromboseq/","status":"emerging","tldr":"An Amsterdam research test that reads RNA inside blood platelets and detected 18 cancer types in a laboratory study, though it often flagged people with other illnesses."},{"id":"epipangi-dx","kind":"drug","name":"EpiPanGI Dx","route":"/drugs/epipangi-dx/","status":"emerging","tldr":"A research blood test that looks for six digestive-system cancers at once and predicts which organ the signal comes from."},{"id":"overc-mcdbt","kind":"drug","name":"OverC Multi-Cancer Detection Blood Test","route":"/drugs/overc-mcdbt/","status":"emerging","tldr":"Burning Rock's methylation blood test from China for five or six cancers, with Breakthrough designations from the US and Chinese regulators but no approval yet."},{"id":"panseer","kind":"drug","name":"PanSeer","route":"/drugs/panseer/","status":"emerging","tldr":"Singlera's methylation blood test, tested on stored samples from a Chinese cohort, that reported finding cancers up to four years before they were diagnosed; it has not been confirmed in a prospective study."},{"id":"oncoseek","kind":"drug","name":"OncoSeek","route":"/drugs/oncoseek/","status":"emerging","tldr":"SeekIn's low-cost protein blood test for 14 cancers, designed for countries that cannot afford DNA sequencing; it finds about six in ten cancers but flags about one in twelve people without cancer."},{"id":"seekincare","kind":"drug","name":"SeekInCare","route":"/drugs/seekincare/","status":"emerging","tldr":"SeekIn's multi-omic blood test that adds DNA sequencing to its protein test; in published studies it found about six to seven in ten cancers and about four in ten at stage I."},{"id":"spot-mas","kind":"drug","name":"SPOT-MAS","route":"/drugs/spot-mas/","status":"emerging","tldr":"Gene Solutions' low-cost blood test from Vietnam; in 9,024 people without symptoms about one in two hundred tested positive and four in ten of those had cancer."},{"id":"trucheck-intelli","kind":"drug","name":"Trucheck Intelli","route":"/drugs/trucheck-intelli/","status":"emerging","tldr":"Datar Cancer Genetics' blood test that looks for clumps of tumour cells, sold privately in the UK; the developer's marketing figures go beyond what its own papers report."},{"id":"anpac-cda","kind":"drug","name":"Cancer Differentiation Analysis (CDA)","route":"/drugs/anpac-cda/","status":"emerging","tldr":"A Chinese blood test that measures physical properties of blood rather than molecules; its developer has since turned to a different business, and the test's status is unclear."},{"id":"n-nose","kind":"drug","name":"N-NOSE","route":"/drugs/n-nose/","status":"emerging","tldr":"A Japanese urine test that uses the sense of smell of tiny worms; it is sold directly to the public in Japan, does not say which cancer, and in a real-world analysis about 2 in 100 people with a positive result were found to have cancer (about 12 in 100 after allowing for cancers the follow-up scan can miss)."},{"id":"cancerfind","kind":"drug","name":"CancerFind","route":"/drugs/cancerfind/","status":"emerging","tldr":"IMBdx's blood test from South Korea, offered at screening centres there, which in a laboratory study detected nine in ten cancers including stage I."},{"id":"ai-cancerch","kind":"drug","name":"ai-CANCERCH","route":"/drugs/ai-cancerch/","status":"emerging","tldr":"GC Genome's blood test from South Korea, launched in 2023 for six cancers, built on a method published with KAIST."},{"id":"aminoindex-cancer-screening","kind":"drug","name":"AminoIndex Cancer Screening (AICS)","route":"/drugs/aminoindex-cancer-screening/","status":"emerging","tldr":"Ajinomoto's Japanese blood test that ranks the risk of several cancers separately from amino acid levels; in a validation of 10,245 people it found 34 cancers."}]}