# OnCo record immune-exclusion (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/immune-exclusion/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "immune-exclusion" ;
  schema:name "Immune exclusion"@en ;
  schema:description "A tumour where the immune cells arrive but are stopped at the edge, held back by scar tissue and signals such as TGF-β."@en ;
  schema:url <https://onco.cc/terms/immune-exclusion/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Tumor_microenvironment> ;
  schema:citation <https://doi.org/10.1038/nature25501> ;
  onco:cancers <https://onco.cc/cancers/pancreatic/> ;
  onco:targets <https://onco.cc/targets/fap/>, <https://onco.cc/targets/vegf/>, <https://onco.cc/targets/cxcr3/> ;
  onco:drugs <https://onco.cc/drugs/retlirafusp-alfa/>, <https://onco.cc/drugs/ficerafusp-alfa/> ;
  onco:pathways <https://onco.cc/pathways/tgf-beta/>, <https://onco.cc/pathways/tumor-microenvironment/>, <https://onco.cc/pathways/pd1-checkpoint/> ;
  onco:terms <https://onco.cc/terms/cold-vs-hot/>, <https://onco.cc/terms/tils/> ;
  onco:trials <https://onco.cc/trials/fortifi-hn01/>, <https://onco.cc/trials/nct04950322/>, <https://onco.cc/trials/nct05300269/>, <https://onco.cc/trials/nct05503888/>, <https://onco.cc/trials/nct05671822/>, <https://onco.cc/trials/nct06679673/>, <https://onco.cc/trials/nct07102901/>, <https://onco.cc/trials/nct07175220/>, <https://onco.cc/trials/nct07478731/>, <https://onco.cc/trials/nct07503639/>, <https://onco.cc/trials/nct07728019/>, <https://onco.cc/trials/nct07752550/>, <https://onco.cc/trials/nct07773363/>, <https://onco.cc/trials/nct07797244/>, <https://onco.cc/trials/nct07802184/>, <https://onco.cc/trials/nct07807163/>, <https://onco.cc/trials/nct07814859/>, <https://onco.cc/trials/nct07815288/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-feig-cxcl12-fap-cafs-t-cell-exclusion-pnas-2013/>, <https://onco.cc/key-papers/paper-balachandran-neoantigen-quality-long-term-survivors-nature-2017/>, <https://onco.cc/key-papers/paper-mariathasan-nature/> .