{"entity":{"id":"singlera","kind":"company","name":"Singlera Genomics","aka":[],"tldr":"A methylation testing company with laboratories in California and Shanghai that published the PanSeer multi-cancer blood test.","summary":"Singlera Genomics, established in 2014 according to its website, with a La Jolla address and a Shanghai subsidiary, published PanSeer, a five-cancer methylation blood test evaluated on stored samples from the Taizhou Longitudinal Study (Nature Communications 2020). Its website now lists single-cancer colorectal and liver tests; its FuSion cohort with Fudan University and the INSPIRE case-control study develop multi-cancer successors.","asOf":"2026-10-29","links":[{"label":"Official website","url":"https://www.singlera.com/"}],"tags":[],"related":[],"cancers":[],"sections":["early-detection","diagnostics"],"technologies":["mced","liquid-biopsy","cfdna-methylation-testing"],"targets":[],"drugs":["panseer"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":["fusion-singlera","inspire-singlera"],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"hq":"La Jolla, CA","country":"US","companyType":"diagnostics","website":"https://www.singlera.com/","founded":2014,"investors":[],"funding":[]},"route":"/companies/singlera/","neighbours":{"section":[{"id":"diagnostics","kind":"section","name":"Diagnostics & Biomarkers","route":"/fronts/diagnostics/"},{"id":"early-detection","kind":"section","name":"Early Detection & Screening","route":"/fronts/early-detection/"}],"technology":[{"id":"cfdna-methylation-testing","kind":"technology","name":"Cell-free DNA methylation tests","route":"/technologies/cfdna-methylation-testing/"},{"id":"liquid-biopsy","kind":"technology","name":"Liquid biopsy (ctDNA)","route":"/technologies/liquid-biopsy/"},{"id":"mced","kind":"technology","name":"Multi-cancer early detection (MCED)","route":"/technologies/mced/"}],"drug":[{"id":"panseer","kind":"drug","name":"PanSeer","route":"/drugs/panseer/"}],"trial":[{"id":"fusion-singlera","kind":"trial","name":"FuSion (Fudan and Singlera pan-cancer screening cohort)","route":"/trials/fusion-singlera/"},{"id":"inspire-singlera","kind":"trial","name":"INSPIRE (Singlera methylation and fragmentomics case-control study)","route":"/trials/inspire-singlera/"}],"paper":[{"id":"paper-panseer-nat-commun-2020","kind":"paper","name":"Non-invasive early detection of cancer four years before conventional diagnosis using a blood test","route":"/key-papers/paper-panseer-nat-commun-2020/"}]}}