{"entity":{"id":"prevent-overc","kind":"trial","name":"PREVENT (OverC in people without symptoms)","aka":["PREVENT"],"tldr":"A Chinese study of about 12,500 people without symptoms that gives them Burning Rock's OverC blood test and follows up positive results.","summary":"PREVENT (NCT05227534) is a single-arm interventional study sponsored by Guangzhou Burning Rock Dx Co., Ltd with West China Hospital. It evaluates the performance of the OverC multi-cancer detection blood test in asymptomatic individuals with cancer risk.\n\nThe registry record, read on 29 October 2026, gives its status as recruiting, with an estimated 12,500 participants, a start on 1 June 2022 and primary completion expected on 1 March 2024.","status":"recruiting","asOf":"2026-10-29","links":[{"label":"ClinicalTrials.gov NCT05227534","url":"https://clinicaltrials.gov/study/NCT05227534"}],"tags":[],"related":[],"cancers":[],"sections":["early-detection"],"technologies":["mced","liquid-biopsy"],"targets":[],"drugs":["overc-mcdbt"],"companies":["burning-rock"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05227534","phase":"not-applicable","setting":"Adults without symptoms but with cancer risk in China, tested with the OverC multi-cancer detection blood test with diagnostic follow-up","sponsor":"Guangzhou Burning Rock Dx Co., Ltd. with West China Hospital","started":"2022-06-01","startedType":"actual","enrolled":12500,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/prevent-overc/","neighbours":{"section":[{"id":"early-detection","kind":"section","name":"Early Detection & Screening","route":"/fronts/early-detection/"}],"technology":[{"id":"liquid-biopsy","kind":"technology","name":"Liquid biopsy (ctDNA)","route":"/technologies/liquid-biopsy/"},{"id":"mced","kind":"technology","name":"Multi-cancer early detection (MCED)","route":"/technologies/mced/"}],"drug":[{"id":"overc-mcdbt","kind":"drug","name":"OverC Multi-Cancer Detection Blood Test","route":"/drugs/overc-mcdbt/"}],"company":[{"id":"burning-rock","kind":"company","name":"Burning Rock Biotech","route":"/companies/burning-rock/"}]}}