{"entity":{"id":"methylscape-co","kind":"trial","name":"METHYLSCAPE-CO (Methylscape test in body fluids, Colombia)","aka":["METHYLSCAPE-CO"],"tldr":"A Colombian study of a rapid test that reads overall DNA methylation in blood, urine or saliva using gold nanoparticles.","summary":"METHYLSCAPE-CO (NCT07741435) is an observational study sponsored by Centro de Tratamiento e Investigación sobre Cáncer, Luis Carlos Sarmiento Angulo. It evaluates the sensitivity and specificity of Methylscape, which uses the different binding of methylated and unmethylated DNA to gold nanoparticles to detect a cancer signal and predict its origin.\n\nThe registry record, read on 29 October 2026, gives its status as recruiting, with an estimated 3,250 participants, a start on 5 June 2025 and primary completion expected on 4 June 2027.","status":"recruiting","asOf":"2026-10-29","links":[{"label":"ClinicalTrials.gov NCT07741435","url":"https://clinicaltrials.gov/study/NCT07741435"}],"tags":[],"related":[],"cancers":[],"sections":["early-detection"],"technologies":["mced","liquid-biopsy"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07741435","phase":"observational","setting":"Patients with biopsy-confirmed solid tumours and controls in Colombia, testing blood, urine and saliva","sponsor":"Centro de Tratamiento e Investigación sobre Cáncer, Luis Carlos Sarmiento Angulo","started":"2025-06-05","startedType":"actual","enrolled":3250,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/methylscape-co/","neighbours":{"section":[{"id":"early-detection","kind":"section","name":"Early Detection & Screening","route":"/fronts/early-detection/"}],"technology":[{"id":"liquid-biopsy","kind":"technology","name":"Liquid biopsy (ctDNA)","route":"/technologies/liquid-biopsy/"},{"id":"mced","kind":"technology","name":"Multi-cancer early detection (MCED)","route":"/technologies/mced/"}]}}