{"entity":{"id":"core-hh","kind":"trial","name":"CORE-HH (Harbinger Health test development and validation)","aka":["CORE-HH","Cancer ORigin Epigenetics-Harbinger Health"],"tldr":"The study of about 8,000 people that Harbinger Health used to build and validate its blood test for many cancers.","summary":"CORE-HH (NCT05435066) is an observational study sponsored by Harbinger Health. It collected blood, tissue and clinical data from people with a variety of cancers and from people without cancer to develop a screening test for early cancer detection.\n\nThe registry record, read on 29 October 2026, gives its status as completed, with 8,038 participants enrolled, a start on 21 June 2022 and primary completion on 11 June 2025.","status":"completed","asOf":"2026-10-29","links":[{"label":"ClinicalTrials.gov NCT05435066","url":"https://clinicaltrials.gov/study/NCT05435066"}],"tags":[],"related":[],"cancers":[],"sections":["early-detection"],"technologies":["mced","liquid-biopsy"],"targets":[],"drugs":["harbinger-resolve"],"companies":["harbinger-health"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05435066","phase":"observational","setting":"People with solid and blood cancers and people without cancer at more than 100 US sites, giving blood and tissue to develop a blood-based multi-cancer screening test","sponsor":"Harbinger Health","started":"2022-06-21","startedType":"actual","enrolled":8038,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/core-hh/","neighbours":{"section":[{"id":"early-detection","kind":"section","name":"Early Detection & Screening","route":"/fronts/early-detection/"}],"technology":[{"id":"liquid-biopsy","kind":"technology","name":"Liquid biopsy (ctDNA)","route":"/technologies/liquid-biopsy/"},{"id":"mced","kind":"technology","name":"Multi-cancer early detection (MCED)","route":"/technologies/mced/"}],"drug":[{"id":"harbinger-resolve","kind":"drug","name":"RESOLVE (Harbinger Health)","route":"/drugs/harbinger-resolve/"}],"company":[{"id":"harbinger-health","kind":"company","name":"Harbinger Health","route":"/companies/harbinger-health/"}],"trial":[{"id":"procares","kind":"trial","name":"PROCARES (Harbinger Health diagnostic aid in people with suspected cancer)","route":"/trials/procares/"}]}}